Oxford COVID-19 Research Praised by Boris Johnson, Blasted by France-Soir

At a media conference this Tuesday, COVID-19 survivor and UK prime minister Boris Johnson announced “the biggest breakthrough yet” regarding therapies for the coronavirus.


“This drug, dexamethasone, can now be made available across the NHS, and we have taken steps to make sure we have enough supplies, even in the event of a second peak.”

“While the chances of dying from COVID-19 have been greatly reduced by this treatment, or significantly reduced by this treatment, it is still far too high.”

The announcement is based on Oxford research that found that 1 death out of around 8 can be prevented by using dexamethasone for ventilated patients, and 1 death out of around 25 can be saved for patients requiring oxygen alone.


Such reductions in death rates are minimal and have to be put into the context of the very high mortality rate of about 25% for hospitalized COVID-19 patients in the UK. 

The side-effects of the drug, when used in ICU, were not mentioned doing this PR exercise, which contrasts with how hydroxychloroquine has been treated in the media over the past months. Steroid administration may have a deleterious effect on the critically ill patient, including hyperglycaemia, hypernatraemia, immunosuppression with increased risk of nosocomial infection, psychiatric side-effects and ICU-acquired weakness.


For certain, the problem of the high UK hospital-level death rates will not be resolved by using dexamethasone, one of the corticosteroid drugs already commonly used for advanced COVID-19 patients around the world.

We already analyzed how ludicrous were the Oxford claims, as much more effective therapies for COVID-19 exist, and actually prevent most patients from reaching this advanced stage of the disease where the odds of dying, at least in UK hospitals, are about 1 out of 4. 

To provide a contrast, at the IHU-Marseille, the hospital level mortality rate is 5%, i.e. 5 times lower than in NHS hospitals.

The Oxford research announcement was actually not only praised by the UK prime minister, but also by the WHO.

“This is great news and I congratulate the Government of the UK, the University of Oxford, and the many hospitals and patients in the UK who have contributed to this lifesaving scientific breakthrough,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General.

>>  2022: the Year of the Omicron

Incidentally, the WHO also announced it was dropping hydroxychloroquine from its SOLIDARITY research trials, a move that was expected, as the RECOVERY clinical trial results offered an opportunity for WHO for doing so, even if many observers now know that the research protocol of the RECOVERY trial, which was giving hydroxychloroquine alone, and at a late stage, was flawed and unlikely to yield any positive therapeutic results.

Note that neither the hydroxychloroquine nor the dexamethasone research by the Oxford scholars has been peer reviewed or published, and there is insufficient data made publicly to thoroughly verify their work. That did not prevent both the UK government and the WHO to fully embrace their findings.

As we have extensively analyzed in this blog, the most effective therapies for COVID-19 involve early treatment, with molecules such as hydroxychloroquine, azithromycin and zinc. Such treatments remain totally disregarded by countries such as the UK as well as by the World Health Organization.

The most extensive research on such hydroxychloroquine-based treatments was conducted on thousands of patients at IHU-Marseille, and demonstrated not only safety, but also considerable effectiveness, with mortality rates below 1%.

Yes, there are research results of HCQ-based treatments on large cohorts of patients showing mortality rates inferior to 1%, while the UK government and the WHO brag about clinical trials, with thousands of patients, where mortality rates are considerably higher.

Two New Articles by France-Soir Blast the Oxford Research

In two articles, the French newspaper France-Soir thoroughly criticizes the Oxford research, and even points at possible criminal wrongdoing by the researchers, one of them actually sharing the podium with the UK prime minister.

France-Soir has adopted an innovative journalistic approach, relying on collaboration with high level scientists to “decrypt” the various scientific announcements and policy decisions during this COVID-19 crisis.

>>  2022: the Year of the Omicron

In the first article, called “CovidPapers, Recovery, the Oxford Connexion” France Soir covers a range of considerations, of which we point to a few in the present article.

  • the explanations provided by the two Oxford professors regarding the high and possibly toxic dosages of hydroxychloroquine given to over 1000 patients don’t make sense, and the assertion by Prof Horby that Prof Landray would have been misquoted is debunked with a recording of the conversation. Actually, the scientific explanation put forward by Prof. Horby, alluding to Amoebic Hepatic Abscess does not seem to make more sense than the one by Prof Landray, who referred to Amoebic Dysentery to justify the dosage. Both academics seem unaware of what constitutes a safe dosage of hydroxychloroquine.
  • in his interview with France Soir, Prof Landray explained that remdesivir had not been tested, presenting as a reason that the medication was not available, yet he did not mention to the journalist interviewing him that the Oxford research programme had already started to offer, since late May, the medication to patients, outside the context of a randomized clinical trial. This is particularly controversial as, to this day, remdesivir remains unproven as a drug for reducing COVID-19 mortality.
  • France Soir sheds light on a web of links between the Oxford researchers and a number of parties that are involved in both the search for medications and vaccines for COVID-19, including the Bill and Melinda Gates foundation, Gilead Science, which produces remdesivir, the pharma giant AstraZeneca, which was said to consider an acquisition or merger with Gilead, the Big Data Institute, funded by a Chinese philanthropist, and even Facebook, through a foundation providing funding for ERGO, another research setting run by Professor Horby.
  • France Soir also looks at the Medicines and Healthcare products Regulatory Agency (MHRA), the UK regulator, and identifies a board member with conflict of interest with AstraZeneca, which “just signed a contract with several other countries to sell 2 or 3 billion euros worth of vaccine doses to European countries.”

To be kept in mind is that hydroxychloroquine is not only a competitor to remdesivir, but also to vaccines. With the pandemic waning in many countries, a number of experts now think there won’t be any need for a vaccine.

>>  2022: the Year of the Omicron

One of these experts is Professor Christian Perronne, a medical doctor specialized in infectious diseases, who has previously held high level positions in the French medical system and at a WHO committee on vaccines.

Professor Perronne clearly stated, in a recent interview on Sud Radio, that there was no need for a vaccine against COVID-19.

Professor Perronne just published a devastating book about the French response to COVID-19, titled “Is There One Mistake They Did Not Do – COVID-19: the Sacred Union of Incompetence and Arrogance.” He believes that some 25,000 deaths could have been avoided in France if the right therapeutic response had been implemented by the authorities. 


The second article in France Soir is titled “Recovery, the good news is a ploy to hide incoherences and grave errors” (in French: “Recovery, la bonne nouvelle est un leurre pour cacher les incohérences et les fautes graves”)

  • the article says that the dexamethasone announcement is not a surprise as the medication is already widely used, yet stresses that it would be abnormal not to use such medication – something that actually took place for a staggering number of 4321 patients in the control group of this Oxford clinical trial.
  • it highlights the fact that it took 8 days for the news to be made public, as the findings were made on June 8, but their revelation was made on June 16 – which can be contrasted with the immediate revelation on June 5 of the findings regarding hydroxychloroquine, while the analysis of the results had been done the day before.
  • the article suggests that there were multiple changes in the research protocol, and varying reported numbers of patients into the trial, which were not made public, and which don’t seem to make sense. The newspaper alleges those changes were not transparent and may not have been made in good faith.
  • it appears that various versions of the research protocol are not public any longer, and the requests by France Soir to receive copies of those have been unanswered.
  • the paper interviewed an unnamed expert in clinical trials, who commented: “this document proves amateurism, ignorance of medical ethics, non-compliance with good practices for clinical trials, and in conclusion, irresponsibility.” 
  • the article concludes that there may be criminal responsibility involved for the two chief investigators of the RECOVERY trial, in what France-Soir suggests will be remembered in history as the #CovidPapers.